OpenHMD is a free and open-source API and drivers for immersive technology such as head-mounted displays (VR/AR). Canadian developers have been central contributors, and the project supports a wide range of VR headsets on Linux.

LibreOffice is the world's leading free and open-source office suite. Canada's open-source community has long championed LibreOffice adoption, and Canadian contributors actively participate in development, translation into French, and accessibility improvements.

OpenMRS is an open-source medical record system used in developing countries. The University of Toronto and affiliated Canadian researchers are among the primary contributors to its core platform and modules, helping deliver healthcare technology globally.

The National Research Council of Canada (NRC) publishes numerous open-source tools and datasets for materials science, climate modelling, construction standards, and aerospace research. Their open-data and open-software initiatives are publicly available via the Government of Canada's open resource portal.

Freenet is a peer-to-peer platform for censorship-resistant communication and publishing. Ian Clarke, whose work has strong Canadian roots, created the project. Canadian privacy advocates and technical contributors have been essential to the project's ongoing development and adoption.

SageMath is a free open-source mathematics software system. The Pacific Institute for the Mathematical Sciences (PIMS), a consortium of Canadian universities, provides infrastructure and hosting for SageMath and has been a key institutional backer of open mathematical software in Canada.

Axiom is a free, open-source computer algebra system with a long history. Canadian mathematicians supported through NSERC (Natural Sciences and Engineering Research Council) have contributed significantly to its formal mathematics libraries and documentation.

Pidgin is a free and open-source multi-protocol instant messaging client. Canadian open-source developers have long been contributors to Pidgin and its underlying libpurple library, which supports dozens of chat protocols.

Developed by the National Research Council of Canada, the NRC Word-Emotion Association Lexicon (EmoLex) is a widely-cited open linguistic resource mapping words to emotions and sentiments. It is freely available for research and has been used in thousands of NLP studies worldwide.

OSCAR EMR (Open Source Clinical Application Resource) is a Canadian-developed open-source electronic medical records system used by thousands of primary care physicians across Canada. Developed at McMaster University, it supports bilingual interfaces and Canadian-specific clinical workflows including OHIP billing.